Shio Ogura is a Japanese high school student, who is visiting Taiwan on a school trip when she is suddenly attacked by monsters. Agents known as "E-Gene Holders" from the government agency DOGOO also arrive, who wield weapons infused with the spirits of historical figures. Shio is revealed to also be an E-Gene Holder when the soul of Oda Nobunaga awakens after she tries to rescue a friend.
Aired: Oct 3, 2017. In the decade since the world became aware of the existence of magic, the world has undergone massive upheaval. However, a boy named Touta lives in seclusion in a rural town far removed from these changes. His ordinary life is highlighted by his magic-using female teacher and his supportive friends. When his tranquil daily life is disrupted, he embarks on a unique adventure.